Does a spare tire make sense? There is no reasonable way to change a tire on your own on a class A motor home on the side of the road without a professional truck tire company. The hydraulics, will of course, lift the bus but even if you have a full size air compressor it will not remove the lug nuts. Because the bus is so heavy the lug nuts are tightened well above the 100 psi that most compressors will deliver, usually somewhere between 500 - 1000 ft lbs. Yes you can buy a long cheater bar but even with that you will likely not be able to even budge the lug nuts. Plus the weight of the mounted tire will be some where between 150 - 200 lbs.
So you have to call a truck tire company anyway. Every truck tire company will bring a new tire and rim no matter what you tell them when you call for the service. They will not come out, lift your bus, remove your lug nuts, put on your spare just to find out that it has a problem of its own or your rim has a problem. If you have a spare, yes they will install it but they will bring a spare and a wheel regardless, so be ready to give them your sizes when you call or don't expect them to come out.
So you have a spare tire taking up a lot of storage space, adding a lot of weight (especially if the tire is mounted - why carry one if its not) tying up your money (for years) and for what reason? The truck tire company is bringing a spare anyway, and you can't change it on your own either.
If it makes sense to you by all means don't let me talk you out of it, but really, ask yourself is it worth it?