Choose trips with less mileage and stick to the old highways and byways that can be really quite scenic.
Modern GPS doesn't mention these roads, but most good road atlases and maps will have the scenic routes marked.
For instance on I-85 going from Georgia to NC, you can hop on highway 11 at the Georgia border then traverse it through the foothills all the way to the edge of NC. The beauty of that highway is stunning. It's actually an old Cherokee trail that was paved. I never tire of that highway.
It's easy to enjoy 45-55 mph on back roads and enjoy some colorful scenery from historic small towns to bucolic fields of cotton and unique sites in between.
I enjoy the putter and sputter of back roads. My stress level is a lot lower, I don't grip the steering wheel too tight (a chronic problem I have to watch out for) and just being able to whimsically stop at special places that crop up when you least expect it.
If you enjoy eating out, on these back roads you will find some seriously good grub at small locally owned places.
Some of the back highways still have scenic pull offs and old fashioned rest areas that consisted of a picnic table, tree and often a creek or river or lake. The dog and I have had many breaks at such awesome quaint places with nature.
I've been known to take an entire day to drive 100 miles because I was provisioning and sightseeing along the way. Once I arrived at my camp which was chose for its remoteness and beauty, I was ready to kick up my heels for communing with nature.
On the back roads, if someone hugs my bumper, I just slow down and pray they go around me, most do.
The only caveat is that you must be mindful of the speed limits near towns. A few still rely on speed traps for income. Mostly they want you to slow down and see the town in hopes you stop and spend some money. 8)