We go from Erie to the Tampa area so it's pretty much the same trip you are considering. In fact we just did it two weeks ago.
We've tried all the options and I-79, Rt 19, I-77, etc is what we keep coming back to. The other routes are enough longer that any advantages are eaten up by the miles. The first 20 miles out of Beckley, WV, on I-77 are terrible. I would do almost anything to avoid that stretch. I tried slowing down and speeding up and about shook my rig apart. Just terrible and they just raised the tolls on top of it.
If you are just going to go to Cleveland to get I-77, you are adding miles and traffic since they come together in Beckley. The section coming through Charleston, on I-77, is pretty curvy and slow. And loads of traffic. Worth avoiding.
