If I was traveling cross country, or even up and down the east coast, from Fl. to New England, I'd rather drive my car like I did this summer, than my motor home like I did last summer. The trip in the MH beat me up pretty bad.
But overall, given the opportunity, I'd rather fly, but that wasn't an option this year, as I needed my car while I was up there for the summer. But when I went up for a long 5 day weekend in April, I flew up, stayed in a hotel and rented a car. Flying up took 2 1/2 hrs. each way, vs driving, which takes 2-3 days each way (or 21 hrs. if driven straight through).
I would rather stay in a campground, with my RV, than a hotel room, but the travel part of driving a large house on wheels for multiple days on end, and then having to turn around, and do it all over again, when heading back home, is what gets to me.....well that and the traffic, and road construction.