I think the only problem with things like growing tomatoes, mobile beer brewing, and such is movement. I also worry about a bottle jiggling out and ending up broken on the floor as a couple of tossed bottles might break open a cabinet door.
Some things, like me, don't travel well which is why I figured out that a real queen bed would work, but these fold out beds or drop down thin ceiling or thin sidewall Murphy beds probably won't work for me beyond one or two nights.
Saw a humorous video of a guy towing a glass garden shed mounted on a trailer. The whole thing collapsed after jiggling it a couple of miles.
Doesn't take much to argue for a diesel MH suspension after the age of 50 or 60. But, yes some people are beyond mortal.