You haven't indicated what you like to do, so suggestions will be all over the map. Virginia Beach and Myrtle Beach (SC) are tourist meccas with nice beaches, but some people avoid them just for that reason - too crowded and too much like city life. Some may like more secluded camping, others may enjoy swimming pools, while still others like museums and cultural exhibits, of which there are many in the Southeast. Some examples that are popular include the Mighty Eighth Air Force museum near Savannah, Calloway Gardens in Georgia, the Biltmore estate in NC, tours of old Savannah, Stone Mountain, etc. Then there are the lighthouses and barrier reefs of the NC coast, Colonial Williamsburg in VA, South of the Border, and so on. Almost anything you can think ofis there somewhere along the way.