That is the essential first question - 5th wheel or class A?
As Don says, so much depends on you that we cannot answer that directly. However a general statement, which is at least partially true in most cases, is that 5th wheel operation tends to favor people who make longer stops, since the setup is usually a bit more involved, but they often have more living space, though not necessarily more (or even as much) on board storage as a class A.
The other half of that generality is that a class A tends to favor the folks who stop for shorter periods, since the setup is relatively quick, often just pull into place, level (auto leveling on many (most?) rigs), extend slides, hook water/sewer/electric and you're done, outside.
So you need to evaluate what kind of operations you expect to do, then evaluate setup requirements vs space/storage/floor plan then, perhaps with specific questions that you want answered evaluate any other things that occur to you.
Reading through the large base of questions answered here, often via searching for specifics, in addition to questions you post for answer/discussion can help get you informed.
Also, I'd visit as many dealers and/or RV shows as you can to look over the various choices, and once you have a general idea of what's out there, spend time in each type (perhaps also different sizes of each type) as if you were actually living in it for a while sitting on the couches/chairs to watch TV (it it comfortable viewing?), to cook in the kitchen (how handy are things? Does it have a pantry or enough storage for pots and pans? How about counter space?).
Maybe you'd sit on the toilet lid, step into the shower with the door closed, check where you'd put your linens, is the bed comfortable, how tough is it to make the bed, etc., etc. etc.
The class A's tend to do better in cold weather, if that's in your plans, but that's not universally true either, but expect the best one's for cold weather are usually the higher end units.
Well, that's a few thoughts for you to evaluate, and I'm sure that others will have other suggestions/viewpoints.