The general advice on lead acid batteries is that cycling them below 50% shortens their service life, and discharging them below 30-40% greatly shortens their service life, where LiFePo4 batteries can be discharged to the 20% level, and only moderately shorten their service life by discharging to 10%.
As to factors other than $/Ah, LiFePo4 has some other nice traits, like much faster charge acceptance, lead acid batteries can take 16+ hours to be fully topped off, as charging rate greatly slows after getting to about 80% capacity, and it can take up to 4-5 hours to get to that initial 80% charge state from a discharged battery. By contrast if you have a large enough charger, a LiFePo4 battery can fully charge in 2-4 hours without shortening its life. This can have a big influence on fuel cost if you are running a generator to top off the battery. LiFePo4 has other nice traits, like much flatter discharge curve with voltages at 13.6-13.1vdc for nearly the top 80% of its charge. Now sure they can be sensitive to abuse, but so can a lead acid, just in different ways, for one LiFePo4 prefer to be stored long term at about half charge, not fully topped off, they also don't like freezing weather, this is why I have moved my battery bank inside my coach, from its exposed position below the entry steps. Though on average I feel the positives greatly outweigh the negatives, and the prices keep dropping, so I decided now was the time to make the jump. Excluding some of the bigger name brand batteries LiFePo4 batteries prices have dropped by probably 30% in the last 6-8 months, and by over 50% in the last 18 months. Even big names like Battleborn have prices down to $799 for a 100ah LiFePo4 battery, this same battery was $949 in April of 2020, with less known name brands having prices down to $300 for a 100 ah battery, just a few months ago it was impossible to find even a lower end 100 ah LiFePo4 battery under about $450.
