Speed is your enemy up there. Alaskan roads have what are called "Frost heaves" which are caused by freezing and ice during Alaska's harsh winters. If you hit a frost heave at high speed you actually can go airborne which is really hard on a vehicle's suspension if you slam down too hard. They're hard to see and sometimes you hit one unexpectedly so you need to drive at Alaskan speeds which are slower. You may drive 350 miles a day in the Lower 48, but you shouldn't even attempt that many miles per day up there to avoid vehicle damage.
Road conditions vary by year. The road construction "season" has to be crammed into a few summer months so you'll likely encounter long stretches of construction. That can mean long delays.
There are more fuel stops these days than a couple of decades ago, but it's still a good idea to purchase the latest Milepost which lists most businesses and points of interest.
Going to Alaska is an adventure with lots to see and do so the longer you can stay, the better. Every little town along the Alcan seems to have a museum and they seldom duplicate contents. One stressed the gold rush and some of the letters written home were fascinating. Whitehorse had a couple of neat museums, including one about Beringia when there was a land mass between North America and Asia. Whitehorse also is where we tasted a lovely jelly made with Fireweed. And, of course, the glaciers are amazing. A tour of the Columbia Icefields Parkway in Canada is a fun adventure. Also, British Columbia has a variety of timber-related factories with tours, and the largest aluminum smelter in North America can be toured. There are interesting native cultural places to visit and you should see a wide variety of wildlife. Oh yes, if you like fresh salmon and halibut you'll think you've died and gone to heaven!
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