My crazy wife (and I say that with utmost love and affection), drove herself, our three kids (3,2, and 6months) along with a friend who had a 1 year old baby, 1700 miles in 23 hours.
They stopped 4 or 5 times for gas, changing diapers, food etc.... but never stopped for rest.
I was sick the whole time they were gone. When I got the phone call to say "we are here", I couldn't believe it. I couldn't have driven that long by my self let alone with four babys and infants to take care of.
When it came time for them to return home, I DEMANDED that they take an extra day and stop at a nice hotel for rest. I was ready to hop on an airplane to go and get them and drive them home (unfortunately no room for me).
The average person is going to spend about 600,000 hours on this planet, take some time and enjoy the scenery.