The engine block, pistons, etc. should still be fine if it has had decent maintenance. Commercial grade diesels like that should be good for 500k-1000k miles between major re-builds. The Allison should still be solid as well. Everything else on the power train is old and worn, unless it has already been replaced. Water pump, radiator, alternator, starter motor, universal joints, suspension, etc. I would want to check those out thoroughly. Hopefully there is documentation of regular service and maybe replacement of some of those things.
Likewise the house has seen 16 years of wear & tear as well as bouncing down the highway for 210k miles. That sort of wear & tear should be discernible to an experenced eye, however. If you don't feel competent to make that judgment, get help from a friend or pro who can.