Are you just looking for trip routing software or wanting information on things to see and do along with the trip routing?
There are several mapping programs, such as Microsoft Streets & Trips, Delorme Street Atlas and I use the Garmin Mapsource to route my trips on the computer and download the route to my Garmin GPS. You can load special "points of interest" (POI's) such as museums, restaurants, amusement parks, etc with the Garmin and I suspect you could do the same with the others too. If you have AAA you can also go to their office and they can give you the tour books with a lot of information on any particular place you are interested in.