In my situation, there simply aren't any disadvantages -- but I planned ahead and made sure I had room for an interior installation in my TT, so temperatures are never a problem. They, along with the charge controller (which needs cooler temps) cables, etc. are in the bunk area which I remodeled. They are completely out of sight, but easily accessible if necessary. I've been using 600 AH of lithium PO4 for over a year (LifeBlue brand, drop ins) without incident. (hope I don't jinx this by saying so). All the charging and drawdown is handled automatically, never have to switch anything off or on. I purchased and installed mine in 2018 when the 30% tax CREDIT for solar was in effect, so the cost was equivalent to LA batts. This credit has decreased now due to . . well you know the answer, but I believe there still is some credit available.
Lithium PO4 s are NOT the fire hazard that other lithium chemistries are. The "thermal runaway" temp for lithium iron phosphate is 518 degrees Fahrenheit -- so a VERY safe battery in that regard.
You can find out everything about these batteries, including fire ratings at
https://batteryuniversity.com/learn/article/lithium_based_batteries
and
https://batteryuniversity.com/learn/article/types_of_lithium_ion
In these 2 articles, you can learn everything about all types of lithium batteries, and it's very interesting reading. It's technical but well written and easily understood.
There are small footprint heat pads that can be placed under the batts to provide temperature control if necessary. I would think this option would work just fine in Class A storage bays. But, you still need to keep the controller at lower temps.
Biggest advantage for me is NO maintenance. No need to keep checking water levels, adding water, etc. etc. As a single full time person, anything, within reason, that minimizes maintenance is a plus.
Linda