Using the tips provided above, the best place to figure out a tire change is in your driveway BEFORE you are faced with the task on the road. One thing no one here has mentioned is that even with the appropriate jack, you might be pulled over on a surface too soft to jack up your unit on. Therefore, you need some SERIOUS blocking in your tool kit, and the yellow plastic blocks people use to level their RVs are not up to the job. Two-by SPF from the lumber store is not enough either; you need to find real 2-inch material of hardwood such as oak. Also, you have to be physically able to crawl under your RV to access the spare (if that's where it's stored) and strong enough to slide it out and replace the flat tire to the same location after it's changed. It is a big help to have a helper, and fortunately, some states have Road Rangers you can call for assistance. But RRs are mainly equipped to change CAR tires and will NOT have a jack that will lift an RV, nor the blocking you need. Personally, I don't trust a blacktop surface to jack against without blocking, but unbroken concrete is probably strong enough. Another thing you should have in your kit is sheets of heavy corrugated cardboard to put down to work on (keeps parts from getting lost/fouled in the dirt) and a pair of coveralls and hand cleaner so you can continue on your way afterwards without dirtying the inside of your RV. As for jacks, I use a bottle jack because it packs smaller and is easier to handle under the RV BUT you will have to have someone weld up a cover for the ram so it spreads the load out and cannot slip. Don't EVER get under get under the RV when it's jacked with the tires removed. The best way to prevent having to change a flat is to physically check your air pressure DAILY in ALL tires BEFORE leaving your campsite, In the event you find a tire low, the first thing to check is that the valve core is not loose, so you need the proper tool for that as well. Others may trust TPMS, but I think they are worthless.