I have (an admittedly older) Crewcab Superduty F250, as well as a small TOAD, Toyota Yaris hatchback, and I can tell you there is a world of difference in agility, the Yaris has a turning radius of 17.1 ft, which hs shorter than the length of the F250 at a bit over 20 ft long. Google puts the turning radius of my F250 at about 30.5 ft, and the turning radius of a 2020 crew cab F250 at 26.5-29 ft depending on trim (I am guessing 4x4 vs 4x2). With the Yaris I could drive in circles on a standard width road so making U turns is trivial, in fact I find myself not reversing in my driveway at home when I have the Yaris here, I just pull forward and make a U turn in the width of the driveway.
Full size pickup trucks are also often not parking garage friendly, once a number of years ago I had to find parking for my F250 at the Texas Medical center in Houston, not only was it hard to get into the parking garage (6'7" clearance with a truck over 6 ft tall), hard to make the turns on ramps, but it ws also hard to find a long enough parking space with only a few in the corners on each level being long enough for it to half way fit.