Ridgway State Park is very nice....especially when there's water in the reservoir. There are also several Forest Service campgrounds in the area in the Uncompaghre forest....very nice if you have a modest sized RV and don't need hookups. Just leave the campfire ingredients at home....most areas in Colorado are under a fire ban due to draught (still).
Highway 550 is a mountain road with steep sections. However, people with trailers do it all the time, as do semis and buses . I don't know if I'd do it if I was a flatlander. And the worst section of the road is probably the section that drops down into Ouray...steep and windy. They don't call Ouray "Little Switzerland" for nothing. But if you have good brakes, it's a gorgeous drive.